Miscarriage is obstetric pathology that is 8-12% of all pregnancies that ended with childbirth. Reasons for miscarriage:
1 Genetic abnormalities – the first two months of the pregnancy approximately 50% of miscarriages are due to chromosomal abnormalities – mostly polyploid (fold increase of the normal number of autosomes). It is important to know that their soil is random and not associated with increased risk of recurrence in subsequent pregnancies.
2. Hormone deficiency – a major cause of spontaneous abortion within the 12th weeks plays a lack of progesterone called. “Protector of pregnancy.” Deficit of progesterone production by the corpus luteum of pregnancy create conditions for defective implantation of a fertilized egg, and poor blood supply, increase retracting function of the uterus and as a consequence – a miscarriage.
3. Infections – a major share as a cause of miscarriage, especially in the early weeks of pregnancy. Leading are “innocent” viral diseases, widely distributed in the autumn and winter. High fever, intoxication, and the direct involvement of the rapidly dividing embryonic cells by inducing can cause early embryonic death and subsequent miscarriage. Especially noteworthy is rubella because of the extremely high rate of adverse fetal abnormalities of the cardiovascular, nervous system and eyes. These specific disabilities apply to pregnant women suffering from rubella in the period to 12 – 14th weeks. For many reasons and misunderstandings in the public mind is the role of the so overexposed. zoonoses – infectious diseases, where the intermediate host is the man – pregnant respectively. In this group of diseases includes toxoplasmosis, listeriosis and brucellosis. It is important to know that they can cause miscarriage and / or congenital birth defects, and only when spent in the current pregnancy, severe form of septic disease.
The group of infectious agents should not be neglects the role of bacterial agents – both in the genital area outside the disease (angina, pneumonia, cystitis, pyelonephritis, etc.) and especially in the genital tract – vagina, cervix, uterine lining, piping and ovaries. From these sites emphasize the most common in diagnostic and therapeutic terms the most blissful and unfortunately – most neglected – the vagina, with inflammatory changes in the lining. Any over-abundant (with a strange odor and color) from the vagina or not accompanied by additional symptoms – redness, swelling, burning, itching and other necessary compulsory gynecological examination at the discretion of microbiological examination and adequate treatment. Otherwise there is a risk of ascending infection with involvement of the sac and subsequent miscarriage.